TY - JOUR ID - 114651 TI - Antimicrobial activities of semi polar-nonpolar and polar secondary metabolites of sponge Dysidea pallescens from Hengam Island, Persian Gulf JO - Iranian Journal of Fisheries Sciences JA - IJFS LA - en SN - 1562-2916 AU - Nazemi, M. AU - Moradi, Y. AU - Rezvani Gilkolai, F. AU - Ahmaditaba, M.A. AU - Gozari, M. AU - Salari, Z. AD - Y1 - 2017 PY - 2017 VL - 17 IS - 1 SP - 200 EP - 209 KW - Antibacterial KW - antifungal KW - Marine sponge KW - Persian Gulf DO - 10.22092/ijfs.2018.114651 N2 - Sponges are the simplest multicellular animals that lack defense mechanisms and rely on chemical defense  that have been used by mankind to develop antimicrobial drugs against diseases.  The present study was designed to demonstrate the antibacterial and antifungal activities of marine sponge Dysidea pallescens semipolar and nonpolar extracts. In this study, D. pallescens were collected from Hengam Island in the Persian Gulf. The extracts were produced by Bligh and Dyer method. Broth Dilution Methods were used to check the antimicrobial activity of D. pallescens extracts against Escherichia coli (ATCC 15224), Pseudomonas aeruginosa (ATCC 25619), Staphylococcus aureus aureus (ATCC 1764), Bacillus subtilis pizizenii (ATCC 6633), Candida albicans (ATCC10231) and Aspergillus fumigates (PTCC5009). The results showed diethyl ether extract has bactericidal activity against S. aureus aureus (MBC=10mg/mL) and B. subtilis spizizenii (MBC=20mg/mL). D. pallescens diethyl ether extract showed a very weak antifungal activity but methanol extract showed fungicidal activity against A. fumigates (MFC=5mg/mL) and C. albicans (MFC=1.5 mg/mL). Therefore nonpolar-semipolar secondary metabolites of D. pallescens solutions in diethyl ether have shown significant antibacterial activity and polar- secondary metabolites solutions in methanol have shown significant antifungal activity.  UR - https://jifro.areeo.ac.ir/article_114651.html L1 - https://jifro.areeo.ac.ir/article_114651_a5dc29515f8f38ff7d5e7a6a3de5ace7.pdf ER -